Topics in Companion Animal Medicine
Volume 24, Issue 4 , Pages 164-174 , November 2009

Small Animal Zoonoses and Immuncompromised Pet Owners

  • Indu Mani, DVM, DSc

      Affiliations

    • Corresponding Author InformationAddress reprint requests to: Indu Mani, DVM, DSc, 121 West Central St, Natick, MA 01760
    • ,
  • James H. Maguire, MD, MPH

References 

  1. Gibbs EPJ. Emerging zoonotic epidemics in the interconnected global community. Vet Rec. 2005;157:673–679
  2. McQuiston JH, Wilson T, Harris S, et al. Importation of dogs into the United States: risks from rabies and other zoonotic diseases. Zoonoses Public Health. 2008;55:421–426
  3. Rabinowitz PM, Gordon Z, Odofin L. Pet-related infections. Am Fam Physician. 2007;76:1314–1322
  4. Kahn LH. Confronting zoonoses, linking human and veterinary medicine. Emerg Infect Dis. 2006;12:556–561
  5. Grant S, Olsen CW. Preventing zoonotic diseases in immunocompromised persons: the role of physicians and veterinarians. Emerg Infect Dis. 1999;5:159–163
  6. Reaser JK, Clark EE, Meyers NM. All creatures great and minute: a public policy primer for companion animal zoonoses. Zoonoses Public Health. 2008;55:385–401
  7. Lefebvre SL, Reid-Smith RJ, Waltner-Toews D. Incidence of acquisition of methicillin-resistant Staphylococcus aureus, Clostridium difficile, and other health-care-associated pathogens by dogs that participate in animal-assisted interventions. J Am Vet Med Assoc. 2009;234:1404–1417
  8. Lefebvre SL, Waltner-Toews D, Peregrine AS, et al. Prevalence of zoonotic agents in dogs visiting hospitalized people in Ontario: implications for infection control. J Hosp Infect. 2006;62:458–466
  9. Baker WS, Gray GC. A review of published reports regarding zoonotic pathogen infection in veterinarians. J Am Vet Med Assoc. 2009;234:1271–1278
  10. Nowotny N, Deutz A. Preventing zoonotic diseases in immunocompromised persons: the role of physicians and veterinarians. [letter to the editor] Emerg Infect Dis. 2000;6:208–209
  11. Hoff GL, Brawley J, Johnson K. Companion animal issues and the physician. South Med J. 1999;92:651–660
  12. Angulo FJ, Glaser CA, Juranek DD: Caring for pets of immunocompromised persons. Symposium at the American Veterinary Medical Association Annual Meeting, Minneapolis, Minnesota, 1993
  13. Abbas AK, Lichtmann AH, Pillai S. Congenital and Acquired Immunodeficiences. In:  Abbas AK,  Lichtmann AH,  Pillai S editor. Cellular and Molecular Immunology. (ed 6). Saunders; 2009;p. 463–488
  14. Fox JG. Enteric bacterial infections. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 339–343
  15. Oswald GP, Twedt DC, Steyn P. Campylobacter jejuni bacteremia and acute cholecystitis in two dogs. J Am Anim Hosp Assoc. 1994;30:165–169
  16. The Center for Food Security and Public Health, Iowa State University, 2009. http://www.cfsph.iastate.edu/Factsheets/pdfs/campylobacteriosis.pdfURL:
  17. Kotton CN. Zoonoses in solid-organ and hematopoietic stem cell transplant recipients. Clin Infect Dis. 2007;44:857–866
  18. Glaser CA, Angulo FJ, Rooney JA. Animal-associated opportunistic infections among persons infected with the human immunodeficiency virus. Clin Infect Dis. 1994;18:14–24
  19. Brenner FW, Villar RG, Angulo FJ, et al: Salmonella nomenclature. J Clin Microbiol 38:2465-2467
  20. Gordon MA. Salmonella infections in immunocompromised adults. J Infect. 2008;56:413–422
  21. Greene CE. Enteric bacterial infections. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 355–360
  22. Lefebvre SL, Reid-Smith R, Boerlin P, et al. Evaluation of the risks of shedding Salmonella and other potential pathogens by therapy dogs fed raw diets in Ontario and Alberta. Zoonoses Public Health. 2008;55:470–480
  23. Finley R, Reid-Smith R, Ribble C, et al. The occurrence and antimicrobial susceptibility of Salmonellae isolated from commercially available canine raw food diets in three Canadian cities. Zoonoses Public Health. 2008;55:462–469
  24. Finley R, Reid-Smith R, Ribble C, et al. The occurrence and anti-microbial susceptibility of Salmonellae isolated from commercially available pig ear pet treats. Zoonoses Public Health. 2008;55:455–461
  25. Hames A, Mumford J, Hale J, et al. Salmonella Michigan soft tissue infection in an immunocompromised child. J Clin Pathol. 2008;61:773–774
  26. Woodard DR, Cone LA, Fostvedt K. Bordetella bronchiseptica infection in patients with AIDS. Clin Infect Dis. 1995;20:193–194
  27. Berkowitz DM, Bechara RI, Wolfenden LL. An unusual cause of cough and dyspnea in an immunocompromised patient. Chest. 2007;131:1599–1602
  28. Ner Z, Ross LA, Horn MV, et al. Bordetella bronchiseptica infection in pediatric lung transplant recipients. Pediatr Transplant. 2003;7:413–417
  29. Dworkin MS, Sullivan PS, Buskin SE, et al. Bordetella bronchiseptica infection in human immunodeficiency virus–infected patients. Clin Infect Dis. 1999;28:1095–1099
  30. Greene CE. Immunocompromised people and shared human and animal infections. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 1058
  31. Just FT, Gilles J, Pradel I, et al: Molecular evidence for Bartonella spp. in cat and dog fleas from Germany and France. Zoonoses Public Health 55:514-520
  32. Inoue K, Maruyama S, Kabeya H, et al. Exotic small mammals as potential reservoirs of zoonotic Bartonella spp. Emerg Infect Dis. 2009;15:526–532
  33. Billeter SA, Levy MG, Chomel BB, et al. Vector transmission of Bartonella species with emphasis on the potential for tick transmission. Med Vet Entomol. 2008;22:1–15
  34. Guptill-Yoran L, Breitschwerdt EB, Chomel BB. Bartonellosis. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 510–524
  35. Brunt J, Guptill L, Kordick DL, et al. American Association of Feline Practitioners 2006 panel report on diagnosis, treatment, and prevention of Bartonella spp. infections. J Feline Med Surg. 2006;8:213–226
  36. Chomel BB, Boulouis HJ, Maruyama S, et al. Bartonella spp. in pets and effect on human health. Emerg Infect Dis. 2006;12:389–394
  37. Accorinti M. Ocular bartonellosis. Int J Med Sci. 2009;6:131–132
  38. Petersen K, Earhart KC, Wallace MR, et al. Bacillary angiomatosis in a patient with chronic lymphocytic leukemia. Infection. 2008;36:480–484
  39. Kahr A, Kerbl R, Gschwandtner K, et al. Visceral manifestation of cat scratch disease in children. A consequence of altered immunological state?. 2000;2:116
  40. Pons I, Sanfeliu I, Nogueras MM, et al. Seroprevalence of Bartonella spp. infection in HIV patients in Catalonia, Spain. BMC Infect Dis. 2008;8:58–63
  41. Pape M, Kollaras P, Mandraveli K, et al. Occurrence of Bartonella henselae and Bartonella quintana among human immunodeficiency virus-infected patients. Ann N Y Acad Sci. 2005;1063:299–301
  42. Janda JM, Graves MH, Lindquist D, et al. Diagnosing Capnocytophaga canimorsus infections. Emerg Infect Dis. 2006;12:340–342
  43. Bonatti H, Rossboth DW, Nachbaur D, et al. A series of infections due to Capnocytophaga spp. in immunosuppressed and immunocompetent patients. Clin Microbiol Infect. 2003;9:380–387
  44. Koch CA, Mabee CL, Robyn JA, et al. Exposure to domestic cats: risk factor for Pasteurella multocida peritonitis in liver cirrhosis?. Am J Gastroenterol. 1996;91:1447–1449
  45. Schmulewitz L, Chandesris MO, Mainardi JL, et al. Invasive Pasteurella multocida sinusitis in a renal transplant patient. Transpl Infect Dis. 2008;10:206–208
  46. Freshwater A. Why your housecat's trite little bite could cause you quite a fright: a study of domestic felines on the occurrence and antibiotic susceptibility of Pasteurella multocida. Zoonoses Public Health. 2008;55:507–513
  47. Eisen RJ, Gage KL. Adaptive strategies of Yersinia pestis to persist during inter-epizootic and epizootic periods. Vet Res. 2008;40:1
  48. Macy D. Plague. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 439–446
  49. Gould LH, Pape J, Ettestad P, et al. Dog-associated risk factors for human plague. Zoonoses Public Health. 2008;55:448–454
  50. Greene CE, DeBey BM. Tularemia. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 446–451
  51. Petersen JM, Mead PS, Schriefer ME. Francisella tularensis: an arthropod-borne pathogen. Vet Res. 2009;40:7
  52. Theiler RN, Rasmussen SA, Treadwell TA, et al. Emerging and zoonotic infections in women. Infect Dis Clin North Am. 2008;22:755–772
  53. Greene CE, Sykes JE, Brown CA, et al. Leptospirosis. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 402–417
  54. Bharti AR, Nally JE, Ricaldi JN, et al. Leptospirosis: a zoonotic disease of global significance. Lancet. 2003;3:757–771
  55. McBride AJA, Athanazio DA, Reis MG, et al. Leptospirosis. Curr Opin Infect Dis. 2005;18:376–386
  56. Vijayachari P, Sugunan AP, Shriram AN. Leptospirosis: an emerging global public health problem. J Biosci. 2008;33:557–569
  57. Bal AM. Unusual clinical manifestations of leptospirosis. J Postgrad Med. 2005;51:179–183
  58. Jones S, Kim T. Fulminant leptospirosis in a patient with human immunodeficiency virus infection: case report and review of the literature. Clin Infect Dis. 2001;33:E31–E33
  59. Adler B, Faine S. Host immunological mechanisms in the resistance of mice to leptospiral infections. Infect Immune. 1977;17:67–72
  60. Sing A, Tuschak C, Hörmansdorfer S. Methicillin-resistant Staphylococcus aureus in a family and its pet cat. N Engl J Med. 2008;358:1200–1201
  61. Van Loo, Huijsdens X, Tiemersma E, et al. Emergence of methicillin-resistant Staphylococcus aureus of animal origin in humans. Emerg Infect Dis. 2007;13:1834–1839
  62. Wulf MWH, Sørum M, van Nes A, et al. Prevalence of methicillin-resistant Staphylococcus aureus among veterinarians: an international study. Clin Microbiol Infect. 2008;14:29–34
  63. Springer B, Orendi U, Much P, et al. Methicillin-resistant Staphylococcus aureus: a new zoonotic agent?. Wien Klin Wochenschr. 2009;121:86–90
  64. Weese JS, Lefebvre SL. Risk factors for methicillin-resistant Staphylococcus aureus colonization in horses admitted to a veterinary teaching hospital. Can Vet J. 2007;48:921–926
  65. Weese JS, Rousseau J, Willey BM, et al. Methicillin-resistant Staphylococcus aureus in horses at a veterinary teaching hospital: frequency, characterization, and association with clinical disease. J Vet Intern Med. 2006;20:182–186
  66. Vengust M, Anderson MEC, Rousseau J, et al. Methicillin-resistant staphylococcal colonization in clinically normal dogs and horses in the community. Lett Appl Microbiol. 2006;43:602–606
  67. Lefebvre SL, Weese JS. Contamination of pet therapy dogs with MRSA and Clostridium difficile. J Hosp Infect. 2009;doi:10.1016/j.jhin.2009.02.019
  68. Epstein CR, Yam WC, Peiris JSM, et al. Methicillin-resistant commensal staphylococci in healthy dogs as a potentialzoonotic reservoir for community-acquired antibiotic resistance. Infect Genet Evol. 2008;9:283–285
  69. Greene CE, Carmichael LE. Canine brucellosis. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 369–381
  70. Lennox AM. Mycobacteriosis in companion psittacine birds: a review. J Avian Med Surg. 2007;21:181–187
  71. Greene CE. Mycobacterial infections. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 462–477
  72. Emmanuel FX, Seagar AL, Doig C, et al. Human and animal infections with Mycobacterium microti, Scotland. Emerg Infect Dis. 2007;13:1924–1927
  73. Jorn KS, Thompson KM, Larson JM, et al. Polly can make you sick: pet bird-associated diseases. Cleve Clin J Med. 2009;76:235–243
  74. Morris PJ. Zoonotic diseases of pet birds. In:  Bonagura JD editors. Kirk's Current Veterinary Therapy XIII. (ed 13). Philadelphia: WB Saunders; 2000;p. 1113–1116
  75. The Center for Food Security and Public Health, Iowa State University. http://www.cfsph.iastate.edu/Factsheets/pdfs/q_fever.pdfURL:
  76. McCaughey C, McKenna J, McKenna C, et al. Human seroprevalence to Coxiella burnetii (Q fever) in Northern Ireland. Zoonoses Public Health. 2008;55:189–194
  77. Nausheen S, Cunha BA. Q fever community-acquired pneumonia in a patient with Crohn's disease on immunosuppressive therapy. Heart Lung. 2007;36:300–303
  78. Greene CE. Miscellaneous viral infections. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 165
  79. Fischer SA, Graham MB, Kuehnert , et al. Transmission of lymphocytic choriomeningitis virus by organ transplantation. N Engl J Med. 2006;354:2235–2249
  80. Amman BR, Pavlin BI, Albariño CG, et al. Pet rodents and fatal lymphocytic choriomeningitis in transplant patients. Emerg Infect Dis. 2007;13:719–725
  81. Crawford PC, Dubovi EJ, Castleman WL, et al. Transmission of equine influenza virus to dogs. Science. 2005;310:482–485
  82. Daly JM, Blunden AS, MacRae S, et al. Transmission of equine influenza virus to English Foxhounds. Emerg Infect Dis. 2008;14:461–464
  83. Payungporn S, Crawford PC, Kouo TS, et al. Influenza A virus (H3N8) in dogs with respiratory disease, Florida. Emerg Infect Dis. 2008;14:902–908
  84. Khanna M, Kumar P, Choudhary K, et al. Emerging influenza virus: a global threat. J Biosci. 2008;33:475–482
  85. Van Reeth K. Avian and swine influenza viruses: our current understanding of the zoonotic risk. Vet Res. 2007;38:243–260
  86. DiGiulio DB, Eckburg PB. Human monkeypox: an emerging zoonosis. Lancet. 2004;4:15–425
  87. Reed KD, Melski JW, Graham MB, et al. The detection of monkeypox in humans in the western hemisphere. N Engl J Med. 2004;350:342–350
  88. Sejvar JJ, Chowdary Y, Schomogyi M. Human monkeypox infection: a family cluster in the Midwestern United States. J Infect Dis. 2004;190:1833–1840
  89. Bennett M, Gaskell RM, Baxby D. Poxvirus infection. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 158–160
  90. Ninove L, Domart Y, Vervel C, et al. Cowpox virus transmission from pet rats to humans, France. Emerg Infect Dis. 2009;15:781–784
  91. Campe H, Zimmermann P, Glos K, et al. Cowpox virus transmission from pet rats to humans, Germany. Emerg Infect Dis. 2009;15:777–780
  92. Overgaauw PAM. Aspects of Toxocara epidemiology: toxocarosis in dogs and cats. Crit Rev Microbiol. 1997;23:233–251
  93. Pivetti-Pezzi P. Ocular toxocariasis. Int J Med Sci. 2009;6:129–130
  94. Katagiri S, Oliveira-Sequeira TCG. Prevalence of dog intestinal parasites and risk perception of zoonotic infection by dog owners in São Paulo State, Brazil. Zoonoses Public Health. 2008;55:406–413
  95. The Center for Food Security and Public Health, Iowa State University. http://www.cfsph.iastate.edu/Factsheets/pdfs/baylisascariasis.pdfURL:
  96. Heukelbach J, Feldmeier H. Epidemiological and clinical characteristics of hookworm-related cutaneous larval migrans. Lancet Infect Dis. 2008;8:302–309
  97. The Center for Food Security and Public Health, Iowa State University. http://www.cfsph.iastate.edu/Factsheets/pdfs/echinococcosis.pdfURL:
  98. Antolová D, Reiterová K, Miterpáková M, et al. The first finding of Echinococcus multilocularis in dogs in Slovakia: an emerging risk for spreading of infection. Zoonoses Public Health. 2009;56:53–58
  99. Molina CP, Ogburn J, Adegboyega P. Infection by Dipylidium caninum in an infant. Arch Pathol Lab Med. 2003;127:e157–e159
  100. Scorza AV, Lappin MR. Detection of Cryptosporidium spp. in feces of cats and dogs in the United States by PCR assay and IFA. J Vet Int Med. 2005;19:437
  101. Pedraza-Díaz S, Amar C, Iversen AM, et al. Unusual Cryptosporidium species recovered from human faeces: first description of Cryptosporidium felis and Cryptosporidium ‘dog type' from patients in England. J Med Microbiol. 2001;50:293–296
  102. Caccio S, Pinter E, Fantini R, et al. Human infection with Cryptosporidium felis: case report and literature review. Emerg Infect Dis. 2002;8:85–86
  103. Shukla R, Giraldo P, Kraliz A, et al. Cryptosporidium spp. and other zoonotic enteric parasites in a sample of domestic dogs and cats in the Niagara region of Ontario. Can Vet J. 2006;47:1179–1184
  104. Hunter PR, Thompson RCA. The zoonotic transmission of Giardia and Cryptosporidium. Int J Parasitol. 2005;35:1181–1190
  105. Cama VA, Ross JM, Crawford S, et al. Differences in clinical manifestations among Cryptosporidium species and subtypes in HIV-infected persons. J Infect Dis. 2007;196:684–691
  106. Smith RP, Chalmers RM, Elwin K, et al. Investigation of the role of companion animals in the zoonotic transmission of cryptosporidiosis. Zoonoses Public Health. 2009;56:24–33
  107. Bajer A. Cryptosporidium and Giardia spp. infections in humans, animals and the environment in Poland. Parasitol Res. 2008;104:1–17
  108. Lappin MR. What you can catch at work I & II. Las Vegas: Western Veterinary Conference; 2008;
  109. Kasprzak W, Pawlowski Z. Zoonotic aspects of giardiasis: a review. Vet Parasitol. 1989;32:101–108
  110. Batchelor DJ, Tzannes S, Graham PA, et al. Detection of endoparasites with zoonotic potential in dogs with gastrointestinal disease in the UK. Transbound Emerg Dis. 2008;55:99–104
  111. Tenter AM, Heckeroth AR, Weiss LM. Toxoplasma gondii: from animals to humans. Int J Parasitol. 2000;30:1217–1258
  112. Kramer L. Human toxoplasmosis and the role of veterinary clinicians. Int J Med Sci. 2009;6:133–134
  113. Dubey JP, Lappin MR. Toxoplasmosis and neosporosis. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 754–768
  114. Etheredge GD, Michael G, Muehlenbein MP, et al. The roles of cats and dogs in the transmission of Toxoplasma infection in Kuna and Embera children in eastern Panama. Rev Panam Salud Publica/Pan Am J Public Health. 2004;16:176–186
  115. Legendre AM. Blastomycosis. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 569–576
  116. Weese JS, Peregrine AS, Armstrong J. Occupational health and safety in small animal veterinary practice: part I—nonparasitic zoonotic diseases. Can Vet J. 2002;43:631–636
  117. Greene CE. Histoplasmosis. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 577–584
  118. Greene RT. Coccidioidomycosis and paracoccidioidomycosis. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 598–608
  119. Kauffman CA. Endemic mycoses: blastomycosis, histoplasmosis, and sporotrichosis. Infect Dis Clin North Am. 2006;20:645–662
  120. Blanco JL, Garcia ME. Immune response to fungal infections. Vet Immunol Immunopathol. 2008;125:47–70
  121. Rosser EJ, Dunstan RW. Sporotrichosis. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 608–612
  122. Oliveira-Neto MP, Mattos M, Lazera M, et al. Zoonotic sporothricosis transmitted by cats in Rio de Janeiro, Brazil: a case report. Dermatol Online J. 2002;8:5
  123. Sharma R, de Hoog S, Presber W, et al. A virulent genotype of Microsporum canis is responsible for the majority of human infections. J Med Microbiol. 2007;56:1377–1385
  124. Fan YM, Huang WM, Li SF, et al. Granulomatous skin infection caused by Malassezia pachydermatis in a dog owner. Arch Dermatol. 2006;142:1181–1184
  125. Malik R, Krockenberger M, O'Brien CR, et al. Cryptococcosis. In:  Greene CE editors. Infectious Diseases of the Dog and Cat. (ed 3). St Louis: Elsevier; 2006;p. 584–598
  126. Nosanchuk JD, Shoham S, Fries BC, et al. Evidence of zoonotic transmission of Cryptococcus neoformans from a pet cockatoo to an immunocompromised patient. Ann Intern Med. 2000;132:205–208
  127. Jarvis JN, Harrison TS. HIV-associated cryptococcal meningitis. AIDS. 2007;21:2119–2129

PII: S1938-9736(09)00069-5

doi: 10.1053/j.tcam.2009.07.002

Topics in Companion Animal Medicine
Volume 24, Issue 4 , Pages 164-174 , November 2009

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